Anti-MIG-6 Antibody [CD02-3E1]

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

MIG-6

Applications

WB

Reactivity

Human, Mouse, Rat

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

WB: 1:1,000

Molecular weight

55 kDa in HepG2 cell lysates

Protein Length

462

Clonă

CD02-3E1

Secvență

MSIAGVAAQEIRVPLKTGFLHNGRAMGNMRKTYWSSRSEFKNNFLNIDPITMAYSLNSSAQERLIPLGHASKSAPMNGHCFAENGPSQKSSLPPLLIPPSENLGPHEEDQVVCGFKKLTVNGVCASTPPLTPIKNSPSLFPCAPLCERGSRPLPPLPISEALSLDDTDCEVEFLTSSDTDFLLEDSTLSDFKYDVPGRRSFRGCGQINYAYFDTPAVSAADLSYVSDQNGGVPDPNPPPPQTHRRLRRSHSGPAGSFNKPAIRISNCCIHRASPNSDEDKPEVPPRVPIPPRPVKPDYRRWSAEVTSSTYSDEDRPPKVPPREPLSPSNSRTPSPKSLPSYLNGVMPPTQSFAPDPKYVSSKALQRQNSEGSASKVPCILPIIENGKKVSSTHYYLLPERPPYLDKYEKFFREAEETNGGAQIQPLPADCGISSATEKPDSKTKMDLGGHVKRKHLSYVVSP

Imunogen

E. coli derived recombinant protein corresponding to amino acids 1-462 of human ERRFI1.

Aminoacizi

aa 1 - 462

Specificitate

This antibody recognises ERBB receptor feedback inhibitor 1, otherwise known as mitogen-inducible gene 6 protein (MIG-6).Expression of ERRFI1 has been shown to increase in the cytoplasm of growing cells. ERRFI1 shares significant homology with the protein product of rat gene-33, expression of which is increased in response to cell stress. ERRFI1 is involved in the regulation of EGFR signaling. Additionally, in response to stress, ERRFI1 has been shown to mediate response to DNA damage through ATM serine/threonine kinases.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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