Anti-Caveolin-3 Antibody [CD05-4A6]

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

Caveolin-3

Applications

WB

Reactivity

Human, Mouse

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

WB: 1:2,000

Molecular weight

19 kDa in mouse heart tissue lysate

Protein Length

83

Clonă

CD05-4A6

Secvență

MMAEEHTDLEAQIVKDIHCKEIDLVNRDPKNINEDIVKVDFEDVIAEPVGTYSFDGVWKVSYTTFTVSKYWCYRLLSTLLGVP

Imunogen

E. coli derived recombinant protein corresponding to amino acids 1-83 of human caveolin 3.

Aminoacizi

aa 1 - 83

Specificitate

This antibody recognises caveolin 3, also known as M-caveolin.Caveolin 3 is the major structural protein of caveolae in muscle. Mutations in the CAV3 gene have been shown to result in a number of different types of myopathies with altered membrane integrity and repair, protein expression, and cell signaling regulation in the cells of muscle tissue. Up-regulation of caveolin in senescent cells attenuates EGF signaling.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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