Anti-PPP2R5E Antibody [IJ01-4C1]

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

PPP2R5E

Applications

WB

Reactivity

Human, Mouse, Rat

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

WB: 1:1,000

Molecular weight

50 kDa in HeLa cell lysates

Protein Length

467

Clonă

IJ01-4C1

Secvență

MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPSSEQPELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVSCNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMNSTMFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIPT

Imunogen

E. coli derived recombinant protein corresponding to amino acids 1-467 of human PPP2R5E.

Aminoacizi

aa 1 - 467

Specificitate

This antibody recognises serine/threonine-protein phosphatase 2A 56-kDa regulatory subunit epsilon isoform, also known as PP2A B subunit isoform B'-epsilon or PP2A B subunit isoform B56-epsilon.PPP2R5E is a member of the phosphatase 2A (PP2A) regulatory subunit B family and functions as a tumor suppressor in human cancers. Studies have also revealed that there may be a correlation between polymorphisms in PP2A subunit genes, including the PPP2R5E gene, and increased risk of lung cancer. Studies have also shown that PPP2R5E may play a role in the proliferation and apoptosis of gastric cancer cells.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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