Anti-GRB14 Antibody [I01-10B4]

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

GRB14

Applications

WB

Reactivity

Human, Mouse, Rat

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG2b

Recommended dilutions

WB: 1:1,000

Molecular weight

60 kDa in K562 cell lysates

Protein Length

175

Clonă

I01-10B4

Secvență

MPSIPNPFPELCCSPFTSVLSADLFPKANSRKKQVIKVYSEDETSRALDVPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIEEENKLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIHGFLHAKEQGKK

Imunogen

E. coli derived recombinant protein corresponding to amino acids 75-249 of human GRB14.

Aminoacizi

aa 75 - 249

Specificitate

This antibody recognises growth factor receptor-bound protein (GRB) 14, also known as GRB14 adapter protein.GRB14 is an adapter molecule of the GRB7/10/14 family. GRB14 has been shown to inhibit insulin receptor (IR) catalytic activity and mediate peptide substrate binding. Members of this GRB family have also been shown to interact with other kinases through their SH2 domain. GRB14 is thought to play a role in the regulation of receptor signaling and modulation of thyroid cancer progression.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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