Anti-STAM2 Antibody [CD01-1D7]

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

STAM2

Applications

WB

Reactivity

Human, Mouse, Rat

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

WB: 1:1,000

Molecular weight

66 kDa in MCF-7 cell lysates

Protein Length

361

Clonă

CD01-1D7

Secvență

KEDEDIAKAIELSLQEQKQQHTETKSLYPSSEIQLNNKVARKVRALYDFEAVEDNELTFKHGEIIIVLDDSDANWWKGENHRGIGLFPSNFVTTNLNIETEAAAVDKLNVIDDDVEEIKKSEPEPVYIDEDKMDRALQVLQSIDPTDSKPDSQDLLDLEDICQQMGPMIDEKLEEIDRKHSELSELNVKVLEALELYNKLVNEAPVYSVYSKLHPPAHYPPASSGVPMQTYPVQSHGGNYMGQSIHQVTVAQSYSLGPDQIGPLRSLPPNVNSSVTAQPAQTSYLSTGQDTVSNPTYMNQNSNLQSATGTTAYTQQMGMSVDMSSYQNTTSNLPQLAGFPVTVPAHPVAQQHTNYHQQPLL

Imunogen

E. coli derived recombinant protein corresponding to amino acids 165-525 of human STAM2.

Aminoacizi

aa 165 - 525

Specificitate

This antibody recognises signal transducing adaptor molecule 2, also known as Hrs-binding protein.STAM2 is a subunit of the ESCRT-0 complex and functions as a regulator of receptor signaling and trafficking. Studies have revealed that STAM2 is highly expressed in the brain and specifically localizes to the nucleus in neurons, suggesting that STAM2 might have a specific function in the nervous system. In gastric cancer, knockdown of STAM2 inhibits cell proliferation and cell migration through affecting the JAK2/STAT3 signaling pathway.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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