Anti-PPP2R5C Antibody [AB01/1C2]

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

PPP2R5C

Applications

WB

Reactivity

Human, Mouse, Rat

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG2a

Recommended dilutions

WB: 1:1,000

Molecular weight

70 kDa in K562 cell lysates

Protein Length

139

Clonă

AB01/1C2

Secvență

YRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQASTMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKALEAHC

Imunogen

E. coli derived recombinant protein corresponding to amino acids 375-513 of human PPP2R5C.

Aminoacizi

aa 375 - 513

Specificitate

This antibody recognises serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, otherwise known as renal carcinoma antigen NY-REN-29.PPP2R5C belongs to the protein phosphatase 2A regulatory subunit B family. Protein phosphatase 2A (PP2A) is one of the four major serine/threonine phosphatases, and is involved in mediating cell growth and division. PP2A is a heterotrimeric protein consisting of a 36 kDa catalytic C subunit, a 65 kDa structural A subunit, and a variable regulatory B subunit. The exact B subunit present determines the substrate selectivity and catalytic activity of PP2A. PPP2R5C has also been shown to regulate ERK signaling through dephosphorylation of ERK.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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