Anti-Peregrin / BRPF1 Antibody

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Descriere

Specificații

Brand

Antibodies

Mărime

100µl

Țintă

Peregrin/BRPF1

Applications

WB

Reactivity

Mouse

Formulation

Supplied in Phosphate Buffered Saline with 0.035% Sodium Azide and 30% Glycerol.

Conjugate

Unconjugated

Host

Rabbit

Clonality

Polyclonal

Product form

Liquid

Concentration

Lot Specific

Isotype

IgG

Recommended dilutions

WB: 1:1,000-1:2,500

Imunogen

A peptide derived from within the C-terminus of mouse BRPF1.

Specificitate

This antibody recognises bromodomain and PHD finger-containing protein 1, also known as peregrin. BRPF1 regulates chromatin by activating the histone acetyltransferases Moz, Morf and Hbo1 and has been shown to play a critical role in a variety of developmental processes including embryonic fibroblast proliferation. BRPF1 is also highly expressed in the central nervous system and plays a crucial role in the development of several important structures, including the hippocampus. BRPF1 has also been shown to play a tumor suppressor role in several malignant tumors. However, BRPF1 may also play an oncogenic role in some cancers such as acute myeloid leukemia (AML).

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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