Anti-OAS1 Antibody

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

OAS1

Applications

WB

Reactivity

Human

Formulation

Supplied in TRIS Buffered Saline, 0.5% BSA and 0.02% Sodium Azide.

Conjugate

Unconjugated

Host

Goat

Clonality

Polyclonal

Product form

Liquid

Concentration

500 µg/ml

Isotype

IgG

Recommended dilutions

WB: 1 µg/ml - 3 µg/ml

Molecular weight

Approximately 50 kDa in cell lysates

Secvență

C-THEYPHFSHRPST

Imunogen

A peptide sequence of C-THEYPHFSHRPST from the internal region (near C terminus) of the protein sequence according to NP_058132.2.

Specificitate

This antibody recognises 2'-5'-oligoadenylate synthase 1 (OAS1), also known as E18/E16 and p46/p42 OAS.OAS1 is a member of the OAS family of genes induced by interferons (IFN) and viruses, and appears to play a role in regulation of signaling pathways during viral infection. The antiviral role of OAS1 appears to be attributed to its ability to detect short double stranded RNAs (dsRNAs). In addition to viral infections, OAS proteins have been implicated in autoimmune diseases and cancer. OAS1 can affect cell migration and high OAS1 mRNA expression has been linked to worse prognosis in patients with breast cancer.

Storage

Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Documentație

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