Anti-CTBP2 Antibody

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Descriere

Specificații

Brand

Antibodies

Mărime

100µl

Țintă

CTBP2

Applications

ChIP, WB

Reactivity

Human, Mouse

Formulation

Supplied in Phosphate Buffered Saline with 0.035% Sodium Azide and 30% Glycerol.

Conjugate

Unconjugated

Host

Rabbit

Clonality

Polyclonal

Product form

Liquid

Concentration

Lot Specific

Isotype

IgG

Recommended dilutions

ChIP: 10 µl per ChIP, WB: 1:500 - 1:1,000

Imunogen

A peptide derived from the C-terminus of human CtBP2.

Specificitate

This antibody recognises C-terminal-binding protein 2.CtBP2 is a protein that in humans is encoded by the CtBP2 gene. In mammals, C-terminal binding proteins (CtBP1 and CtBP2) function as transcriptional corepressors. CtBPs bind to many different DNA-binding proteins as well as other co-repressors, such as friend of GATA (Fog), that are themselves bound to DNA-binding proteins. CtBPs are also able to dimerize and multimerize to bridge larger transcriptional complexes and function as scaffold proteins that enable the assembly of gene repression complexes. In mammals, there are two distinct isoforms of CtBP2; a 56 kDa isoform that functions as a transcriptional repressor, and a 106 kDa isoform that is a major component of specialized synapses known as synaptic ribbons.recognises both isoforms 1 and 2 of CtBP2.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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