Anti-Histone H2A.J Antibody

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Descriere

Specificații

Brand

Antibodies

Mărime

100µl

Țintă

Histone H2A.J

Applications

WB

Reactivity

Human, Mouse

Formulation

Supplied in Phosphate Buffered Saline with 0.035% Sodium Azide and 30% Glycerol.

Conjugate

Unconjugated

Host

Rabbit

Clonality

Polyclonal

Product form

Liquid

Concentration

Lot Specific

Isotype

IgG

Recommended dilutions

WB: 1:1,000, WB: 1:500 - 1:2500

Protein Length

8

Secvență

ESQKTKSK

Imunogen

A peptide corresponding to amino acids 122-129 of human histone H2A.J.

Aminoacizi

aa 122 - 129

Specificitate

This antibody recognises Histone H2A.J.Histone H2A.J is a 16 kDa variant of the H2A histone. Histones are nuclear proteins that regulate the nucleosome structure of the chromosomal fibres in eukaryotic cells. Nucleosomes are the smallest subunit of chromatin and are made up of 146 bp of DNA wrapped around an octamer comprised of pairs of the four core histones (H2A, H2B, H3, and H4) (Smith, 1991). Histone H2A.J may be linked to senescence and upregulation of the expression of inflammatory genes. Histone H2A.J may therefore play a role in chronic inflammation and age-related diseases.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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