Anti-ELK1 Antibody

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Descriere

Specificații

Brand

Antibodies

Mărime

100µl

Țintă

ELK1

Applications

IP, WB

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with 0.035% Sodium Azide and 30% Glycerol.

Conjugate

Unconjugated

Host

Rabbit

Clonality

Polyclonal

Product form

Liquid

Concentration

Lot Specific

Isotype

IgG

Recommended dilutions

IP: 10 µl per IP, WB: 1:500 - 1:1,000

Imunogen

A peptide derived from within the C-terminus of human ELK-1.

Specificitate

This antibody recognises ETS domain-containing protein ELK-1.ELK-1 is a protein that functions as a transcription activator. ELK-1 is a member of a subclass of the ETS family known as ternary complex factors (TCFs). TCFs are characterized by a common protein domain that regulates DNA binding to target sequences. In non-neuronal cells, ELK-1 is expressed in the nucleus. However, in mature neurons ELK-1 is present in the cytoplasm as well as the nucleus and plays a crucial role in a number of neurological processes, including the formation of long-term memory and drug addiction. ELK-1 expression has been implicated in a number of diseases, including Down syndrome, Alzheimer’s disease and depression.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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