Anti-Histone H2A (phospho Thr120) Antibody

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

Histone H2A

Applications

WB

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with 0.035% Sodium Azide and 30% Glycerol.

Conjugate

Unconjugated

Host

Rabbit

Clonality

Polyclonal

Product form

Liquid

Concentration

Lot Specific

Isotype

IgG

Recommended dilutions

WB: 1 µg/ml, WB: 0.5 µg/ml - 2 µg/ml

Imunogen

A peptide containing phosphorylated threonine 120 of human histone H2A.

Specificitate

This antibody recognises Histone H2A when phosphorylated at threonine 120.Histone H2A is one of the four core histones that make up the nucleosome core particle. Nucleosomes are the smallest subunit of chromatin and are made up of 146 bp of DNA wrapped around an octamer comprised of pairs of the four core histones (H2A, H2B, H3, and H4) (Smith, 1991). Phosphorylation of histone H2A at threonine 120 promotes oncogenic transformation in human cancer cell lines via upregulation of cyclin D1. Wide species cross-reactivity is expected from Rabbit anti Human histone H2A (pThr120) antibody based on sequence homology.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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