Anti-EHMT1 / GLP Antibody

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

EHMT1/GLP

Applications

WB

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with 0.035% Sodium Azide and 30% Glycerol.

Conjugate

Unconjugated

Host

Rabbit

Clonality

Polyclonal

Product form

Liquid

Concentration

Lot Specific

Isotype

IgG

Recommended dilutions

WB: 1 µg/ml - 2 µg/ml

Imunogen

A peptide derived from the N-terminus of human EHMT1.

Specificitate

This antibody recognises euchromatic histone-lysine N-methyltransferase 1, also known as G9a-like protein (GLP).EHMT1 shares an evolutionary conserved SET domain with G9A, a histone methyltransferase enzyme. EHMT1 and G9A function exclusively as a heteromeric complex. G9A and EHMT1 also share a region containing ankryin repeats, involved in protein-protein interactions. The G9A/EHMT1 complex is able to methylate a wide range of non-histone proteins including transcription factors such as p53. As a result of their non-histone protein methyltransferase activity, both G9A and EHMT1 play a role in a wide range of cellular processes including cellular response to environmental stimuli, the establishment and maintenance of cell identity, and cell cycle regulation.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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