Anti-ELF1 Antibody

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

ELF1

Applications

WB, IHC-P

Reactivity

Human, Mouse

Formulation

Supplied in TRIS Buffered Saline, 0.5% BSA and 0.02% Sodium Azide.

Conjugate

Unconjugated

Host

Goat

Clonality

Polyclonal

Product form

Liquid

Concentration

500 µg/ml

Isotype

IgG

Recommended dilutions

IHC-P: 2.5 µg/ml, WB: 0.03 µg/ml - 0.1 µg/ml

Molecular weight

Approximately 70 kDa in cell lysates

Secvență

C-AMKQNELLEPNSF

Imunogen

A peptide sequence of C-AMKQNELLEPNSF from the C-terminus of the protein sequence according to NP_758961.1; NP_001138825.1.

Specificitate

This antibody recognises ETS-related transcription factor Elf-1, also known as E74-like factor 1 (ELF1).ELF1 is a small zinc-finger protein conserved in eukaryotes and some archaea. ELF1 is ubiquitously expressed in human cells and is a member of the ETS family of transcription factors and appears to act downstream of the DNA damage response pathway. In cancer, ELF1 appears to have oncogenic and tumor suppressive functions depending on context. ELF1 appears to play an antiviral role, with lower levels of ELF1 reducing host defense against the influenza A virus.

Storage

Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Documentație

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