Anti-TEM7 Antibody

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

TEM7

Applications

WB, IHC-P

Reactivity

Human, Mouse, Rat

Formulation

Supplied in phosphate-buffered saline with 0.02% Sodium Azide.

Conjugate

Unconjugated

Host

Rabbit

Clonality

Polyclonal

Product form

Liquid

Concentration

1 mg/ml

Isotype

IgG

Recommended dilutions

IHC-P 1: 2.5 µg/ml, WB: 0.5 - 1 µg/ml

Molecular weight

Approximately 56 kDa in rat liver cell lysates.

Protein Length

16

Imunogen

A peptide corresponding to 16 amino acids near the center of human TEM7.

Specificitate

This antibody recognises human Tumour endothelial marker 7, also known as TEM7, a 55.8 kDa protein belonging to the plexin family.TEM7 is strongly expressed in endothelial cells from colorectal cancer and from primary cancers of the lung, liver, brain, breast and pancreas. High expression of TEM7 is associated with metastasis and poor survival of patients with osteogenic sarcoma.There appear to be at least four isoforms of TEM7 which include membrane bound, secreted and intracellular forms. TEM7 is not detectable in endothelial cells from normal tissues.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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