Anti-Neurokinin B Receptor Antibody

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

Neurokinin B Receptor

Applications

WB, IHC-P

Reactivity

Human, Mouse

Formulation

Supplied in phosphate-buffered saline with 0.02% Sodium Azide.

Conjugate

Unconjugated

Host

Rabbit

Clonality

Polyclonal

Product form

Liquid

Concentration

1 mg/ml

Isotype

IgG

Recommended dilutions

IHC-P 1: 5 µg/ml, WB: 0.5 - 1 µg/ml

Molecular weight

Approximately 46 kDa in RAW264.7 cell lysates.

Protein Length

18

Imunogen

A peptide corresponding to 18 amino acids near the centre of human TACR3.

Specificitate

This antibody recognises human TACR3 otherwise known as NK3 Receptor (NK3R), a 52.2 kDa multi-pass membrane protein belonging to the G-protein coupled receptor 1 family.TACR3 is a receptor for the tachykinin neuropeptide, neuromedin-k otherwise known as neurokinin B and is highly expressed in the supraoptic and paraventricular nuclei. Following binding of its ligand, NK3R activates a phosphatidylinositol-calcium second messenger system, and it is likely that these signals lead to the release of vasopressin and oxytocin into the circulation. TACR3 is involved in learning and memory. Rabbit anti Human TACR3 antibody (AHP1492) does not recognize NK1R or NK2R.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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