Anti-CXCL10 / IP-10 Antibody [D03-4F4] (Biotin)

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

CXCL10 / IP-10

Applications

ELISA

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.

Conjugate

Biotin

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

100 µg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

ELISA: 1 µg/ml.

Clonă

D03-4F4

Imunogen

E. coli derived recombinant human full length CXCL10 (Val22-Pro98).

Specificitate

This antibody recognises Chemokine C-X-C ligand 10 (CXCL10), also known as interferon-?-inducible protein 10 (IP-10), is a member of the C-X-C subfamily of chemokines. CXCL10 can be secreted by leukocytes, neutrophils, monocytes, endothelial cells, fibroblasts, thyrocytes and keratinocytes. CXCL10 plays a role in the recruitment of immune cells expressing its specific receptor, CXCR3. Beyond regulating immune cell migration, CXCL10 also plays a role in regulating cell growth and angiogenesis inhibition during tissue injury, development and maintenance.Under normal physiological conditions, CXCL10 is usually undetectable in most non-lymphoid tissues. Only upon induction of an immunoinflammatory response through infection or injury is CXCL10 then detected. As such, CXCL10 has been used as a biomarker of disease severity and as a prognostic indicator for various renal diseases. This biotinylated Mouse anti Human CXCL10 antibody, clone D03-4F4 (MCA6189B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human CXCL10 antibody, clone A01-2G1 (MCA6188GA) as the capture antibody.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Documentație

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