Anti-Tissue Plasminogen Activator Antibody [D11-7G8]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

Tissue Plasminogen Activator

Applications

ELISA

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

ELISA: 1 µg/ml.

Clonă

D11-7G8

Imunogen

Purified native human tPA.

Specificitate

This antibody recognises tissue type plasminogen activator (tPA) also known as PLAT. tPA is a serine protease that in the intravascular space, catalyzes the conversion of plasminogen to plasmin. tPA is expressed in various cell types including endothelial cells, glial cells and neurons. Within the brain tPA plays a role in synaptic plasticity, detection and adaptation to metabolic stress, modulation of the blood-brain barrier permeability and remodeling of the extracellular matrix. The purified Mouse anti Human tPA antibody, clone D11-7G8 (MCA62682GA) can be used as a capture antibody in a sandwich ELISA with the biotinylated Mouse anti Human tPA antibody, clone D12-9A7 (MCA6283B) as the detection antibody.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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