Anti-Adiponectin Antibody [D02-7B10] (Biotin)

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

Adiponectin

Applications

ELISA

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.

Conjugate

Biotin

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

100 µg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

ELISA: 1 µg/ml.

Clonă

D02-7B10

Imunogen

E. coli derived recombinant human adiponectin (Glu19-Asn244).

Specificitate

This antibody recognises adiponectin, also known as ACRP30, apM-1, ADIPOQ. Adiponectin is a fat-derived hormone which suppresses glucose production in the liver and enhances fatty acid oxidation in skeletal muscle, and acts as a messenger to allow communication between adipose tissue and other organs. Adiponectin can elicit several downstream signaling events, including the insulin signaling pathway. Anti-diabetic, anti-inflammatory, and anti-atherogenic effects of adiponectin have been identified, and the protein sensitizes cells to insulin. Decreased adiponecin levels may play a role in development of type 2 diabetes, and therefore, adiponectin has been suggested as a potential therapeutic target for diabetes. The biotinylated Mouse anti Human adiponectin antibody, clone D02-7B10 (MCA6175B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human adiponectin antibody, clone D05-9C7 (MCA6174GA) as the capture antibody.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Documentație

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