Anti-TNF alpha Antibody [B-C7]

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Descriere

Specificații

Brand

Antibodies

Mărime

500µg

Țintă

TNF Alpha

Applications

ELISA

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein A affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Cross reactivity

This antibody does not cross-react with Mouse.

Clonă

B-C7

Imunogen

Recombinant human TNF-alpha.

Specificitate

This antibody recognises human tumor necrosis factor, also known as Cachectin or Tumor necrosis factor ligand superfamily member 2. TNFa exists as a 233 amino acid membrane bound form, a single pass type II transmembrane protein which can be cleaved between residues 76 and 77 by ADAM17, also known as CD156b to yield the 157 amino acid soluble form of TNFa (UniProt: P01375).recognises both natural and bacterially producted recombinant human TNF-alpha and has an affinity of Kd = 0.5nM. Mouse anti Human TNF alpha antibody, clone B-C7 demonstrates neutralising activity against human TNF-alpha. Removal of sodium azide is recommended prior to functional assays.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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