Anti-TCR gamma/delta Antibody [B1]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

TCR gamma/delta

Applications

Flow Cytometry, IHC-Fr, IHC-P

Reactivity

Human, Primate

Formulation

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein A affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Purity

> 95% (by SDS-PAGE).

Clonă

B1

Specificitate

This antibody recognises TCR gamma/delta, a T cell receptor expressed by a small subset of T cells. In healthy individuals these TCR gamma/delta cells account for 1-10% of peripheral blood lymphocytes. TCR gamma/delta is composed of disulfide bonded gamma and delta chains that can bind directly to pathogen derived glycoprotein's or non-classical MHC molecules on tumor cells. This clone B1 has been used as a blocking antibody in experiments to examine the recognition of tumor cells by TCR gamma/delta cells. These experiments supported the hypothesis that innate NK receptors on gamma/delta cells can also bind and recognize tumor cells.

Storage

Store undiluted at 4°C. Do not freeze!

Documentație

• Fișă tehnică (PDF)se deschide pe site-ul producătorului