Anti-Eotaxin 2 Antibody [B01-5E2] (Biotin)

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

Eotaxin 2

Applications

ELISA

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.

Conjugate

Biotin

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

100 µg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

ELISA: 1 µg/ml.

Clonă

B01-5E2

Imunogen

E. coli derived recombinant human full length CCL24 (Val27-Ala104).

Specificitate

This antibody recognises C-C motif chemokine 24, also known as Eotaxin-2, CK-beta-6, and MPIF-2. CCL24 is a chemokine which is induced in macophages and promotes recruitment and activation of immune cells including eosinophils, basophils, and Th2 cells by interacting with the CCR3 receptor. Therefore, CCL24 expression increases during inflammatory disease and allergic reaction, and CCL24 has been shown to perpetuate allergic reaction. CCL24 is involved with proinflammatory and profibrotic reactions, particularly fibrosis of the skin and lungs. Furthermore, CCL24 plays a role in intrahepatic fibrosis and liver damage. Elevated CCL24 has been associated with primary colorectal and liver metastatic tumors. The biotinylated Mouse anti Human CCL24 antibody, clone B01-5E2 (MCA6183B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human CCL24 antibody, clone C05-2B5 (MCA6182GA) as the capture antibody.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Documentație

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