Anti-PITX2 / RGS Antibody

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Descriere

Specificații

Brand

Antibodies

Mărime

100µl

Țintă

PITX2/RGS

Applications

WB

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with 0.035% Sodium Azide and 30% Glycerol.

Conjugate

Unconjugated

Host

Rabbit

Clonality

Polyclonal

Product form

Liquid

Concentration

Lot Specific

Isotype

IgG

Recommended dilutions

WB: 1:500

Imunogen

A peptide derived from within the N-terminus of human PITX2.

Specificitate

This antibody recognises pituitary homeobox 2, also known as paired-like homeodomain transcription factor 2.PITX2 is a member of the RIEG/PITX homeobox family and functions as a transcription factor. PITX2 regulates the expression of procollagen lysyl hydroxylase; involved in the development of teeth, eyes, and abdominal organs. Mutations in the PTIX2 gene have been linked to Axenfeld-Rieger syndrome (ARS) (Héon et al. 1995). Aberrant levels of PITX2 have also been observed in cancers like thyroid, ovarian, and colon cancer.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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