Anti-KAT13A / SRC1 Antibody [C02/13A7]

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

KAT13A/SRC1

Applications

WB

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

WB: 1:2,000

Molecular weight

Approximately 185 kDa in HEK293 cell lysates.

Protein Length

470

Clonă

C02/13A7

Secvență

MSGLGDSSSDPANPDSHKRKGSPCDTLASSTEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTVDQIQLMKRMEQEKSTTDDDVQKSDISSSSQGVIEKESLGPLLLEALDGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNGVPWPQEATRRNSHTFNCRMLIHPPDEPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQSCLICIARRLPRPPAITGVESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMGIHIIDREHSGLSPQDDTNSGMSIPRVNPSVNPSISPAHGVARSSTLPPSNSNMVSTRINRQQSSDLHSSSHSNSSNSQGSFGCSPGSQIVANVALNQGQASSQSSNPSLN

Imunogen

E. coli derived recombinant protein corresponding to amino acids 1-470 of human NCOA1.

Aminoacizi

aa 1 - 470

Specificitate

This antibody recognises Nuclear receptor coactivator 1 protein, also known as NCoA-1.NCOA1 is part of the p160 steroid receptor coactivator (SRC) family, and plays a crucial role in gene regulation. Dysregulation of NCOA1 results in progression and initiation of different cancers. Coactivators such as NCOA1 interact with sex steroid receptors such as estrogen receptor (ER) and androgen receptor (AR). Due to this interaction, there has been a great interest in study of breast and prostate cancers, and has generally been seen to be high in these cancers.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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