Anti-CAMKK2 Antibody [AB01/3H6]

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

CAMKK2

Applications

WB

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

WB: 1:2,000

Molecular weight

Approximately 75 and 77 kDa in K562 cell lysates.

Protein Length

446

Clonă

AB01/3H6

Secvență

MSSCVSSQPSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRKLSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV

Imunogen

E. coli derived recombinant protein corresponding to amino acids 1-446 of human CaMKK II.

Aminoacizi

aa 1 - 446

Specificitate

This antibody recognises calcium/calmodulin-dependant protein kinase kinase 2.CaMKK II is part of the serine/threonine kinase family, and is involved in the activation and phosphorylation of targets such as CAMKI, CAMKIV and AMPK. The facilitation of these targets increases the progression of cancer. CamKK II is involved in the regulation of inflammatory conditions such as prostate and hepatocellular cancers, as well as conditions like obesity and insulin resistance.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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