Anti-Feline Leukaemia Virus p15E Antibody [PF6J-2A1]

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Descriere

Specificații

Brand

Antibodies

Mărime

250µg

Țintă

Feline Leukaemia Virus p15E

Applications

WB, IHC-P, IP

Reactivity

Viral

Formulation

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein A affinity chromatography of tissue culture supernatant.

Isotype

IgG2a

Recommended dilutions

WB: 1:2,000

Molecular weight

Approximately 15 kDa and 20 kDa under reducing conditions.

Clonă

PF6J-2A1

Specificitate

This antibody recognises an epitope within the amino-terminal domain of both the 20 kDa full-length (including intracellular sequence), and the 15k Da truncated forms, of feline leukaemia virus (FeLV) p15e transmembrane envelope protein.Persistent infection of cats with the oncoretrovirus FeLV can result in the non-neoplastic condition known as FeLV-associated enteritis (FAE). There is strong expression of the major FeLV proteins p15e and gp70 in intestinal crypt epithelial cells of cats with FAE, compared to FeLV-positive cats without intestinal alterations, thereby suggesting a pathogenic role for these envelope proteins/precursors in FAE.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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