Anti-MHC Class II Antibody [PF6J-6D]

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Descriere

Specificații

Brand

Antibodies

Mărime

250µg

Țintă

MHC Class II

Applications

WB, IHC-P, ELISA, Flow Cytometry

Reactivity

Feline

Formulation

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein A affinity chromatography of tissue culture supernatant.

Isotype

IgG2b

Recommended dilutions

Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Molecular weight

Approximately 29-31 kDa on fractionated cat lymphocyte cell lysates under non-reducing conditions.

Clonă

PF6J-6D

Specificitate

This antibody recognises an epitope within the ~29-31 kDa beta chain region of cat MHC class II molecules which are expressed by antigen presenting cells, B cells, monocytes and activated T lymphocytes.The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In cats, this is referred to as the feline leukocyte antigen (FLA) region.The complex retrovirus FIV (feline immunodeficiency virus), is responsible for a progressive and debilitating immune deficiency syndrome in domestic cats, similar to that caused by the human Immunodeficiency virus (HIV), the intensity of MHC Class II expression on cat lymphocyte membranes has been found to vary in association with feline retrovirus infections.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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