Anti-CD134 / OX40L Antibody [7D6]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

CD134 / OX40L

Applications

WB, Flow Cytometry

Reactivity

Feline

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein A affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

WB: 1 µg/ml, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Molecular weight

Approximately 43 kDa.

Cross reactivity

This antibody does not cross-react with Mouse.

Clonă

7D6

Imunogen

CHO derived feline CD134-Fc fusion protein.

Specificitate

This antibody recognises feline CD134, otherwise known as OX40, a 43 kDa type I membrane protein and member of the tumor necrosis factor receptor superfamily, expressed predominantly by CD4+ activated T cells, and a key regulator of T cell-dependent immune responses.CD134 has been identified as the receptor for the OX40 ligand, CD252, expressed by activated B cells, acting as a co-stimulatory signal for the stimulation and secretion of immunoglobulins. CD134 has also been identified as a binding receptor for Feline Immunodeficiency Virus (FIV), acting along with CXC chemokine receptor 4 (CXCR4) to facilitate the entry of the virus into CD4+ primary target cells.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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