Anti-CD11b Antibody [ED8]

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Descriere

Specificații

Brand

Antibodies

Mărime

250µg

Țintă

CD11b

Applications

Flow Cytometry, IHC-Fr

Reactivity

Rat

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Clonă

ED8

Imunogen

Rat spleen cell homogenate with Freund's complete adjuvant.

Specificitate

This antibody recognises a membrane antigen on rat macrophages, monocytes, dendritic cells and granulocytes. It also recognises small ramified microglia in the central nervous system. No other cell types are positive for ED8. The recognized antigen is a heterodimer consisting of ~160 and ~95 kDa, belonging to the family of adhesion molecules CD11b/CD18, also designated as Mac-1 antigen or CR3. Mouse anti Rat CD11b antibody, clones ED7 (MCA618R) and ED8 may recognize closely related epitopes on the same molecule. Both clones ED7 and ED8 induce homotypic aggregation of granulocytes (Draskovic-Pavlovic et al. 1999).

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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