Anti-CD11b Antibody [ED7]

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Descriere

Specificații

Brand

Antibodies

Mărime

250µg

Țintă

CD11b

Applications

IHC-Fr, Flow Cytometry, Functional Assays

Reactivity

Rat

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

500 µg/ml

Purification

Protein A affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

IHC-Fr 2: 1:500, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl.

Clonă

ED7

Imunogen

Rat spleen cell homogenate.

Specificitate

This antibody recognises a membrane antigen on rat macrophages, monocytes, dendritic cells and granulocytes. Like ED8, ED7 recognises small ramified microglia in the central nervous system. No other cell types are positive for ED7, except for the cilia of the bronchus epithelium. The recognised antigen is a heterodimer (~160 and ~95 kDa) belonging to the family of adhesion molecules (CD11b/CD18). ED7 and ED8 may recognise closely related epitopes on the same molecule. ED7 and ED8 have been shown to induce homotypic aggregation of granulocytes.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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