Anti-C3b Antibody [H11]

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Descriere

Specificații

Brand

Antibodies

Mărime

50µg

Țintă

C3b

Applications

WB, IHC-Fr

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with 0.2% BSA and 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Lyophilized

Concentration

50 µg/ml after reconstitution.

Purification

Protein A affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

IHC-Fr: 1:10

Reconstitution

Reconstitute with 1 ml of distilled water. Care should be taken during reconstitution as the antibody may appear as a film at the bottom of the vial. Gently mix after reconstitution.

Clonă

H11

Imunogen

Human C3b.

Specificitate

This antibody recognises human C3b, part of the complement system. C3 is cleaved by C3-convertase creating C3a and C3b, which binds to the surface of pathogens leading to their destruction by phagocytic cells. recognises a determinant present on native (circulating) C3 and on the fragments C3b and C3c. The antibody is directed to a determinant present on the betachain of the C3 molecule (Western blot). It does not react with the anaphylatoxin C3a or the fragment C3d and does not inhibit the haemolytic function of C3.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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