Anti-TNF Receptor I Antibody [H398]

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărimi disponibile

25µg · 200µg

Țintă

TNF Receptor I

Applications

ELISA, RIA

Reactivity

Human, Rabbit

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein A affinity chromatography of tissue culture supernatant.

Isotype

IgG2a

Clonă

H398

Imunogen

Purified human tumour necrosis factor receptor type 1.

Specificitate

This antibody recognises an extracellular domain of the ~55 kDa human TNF receptor (p55, TNF-R1, CD120a). No binding occurs to the ~75 kDa TNF receptor (CD120b). CD120a is weakly expressed by monocytes and granulocytes. Mouse anti Human CD120a antibody, clone H398 may be used to detect high levels of TNFR1, in western blotting under reducing conditions, such as recombinant material, but it is not suitable for detection of TNFR1 in normal cells in this application. Mouse anti Human CD120a antibody, clone H398 inhibits the biological activity of both natural and recombinant human TNFalpha and TNFbeta (Thoma et al. 1990 and Dri et al. 1999). Mouse anti Human CD120a antibody, clone H398 is routinely tested in flow cytometry on human peripheral blood monocytes.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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