Anti-TLR4 Antibody [HTA125]

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărimi disponibile

100µg · 200µg

Țintă

TLR4

Applications

Flow Cytometry, IP

Reactivity

Human, Rhesus Monkey, Guinea Pig, Pig, Dog, Bovine

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG2a

Recommended dilutions

Flow Cytometry: 1:10 - 1:50 Pack Size: 0.1 mg 1:25 Pack Size: 0.2 mg, Use 10µl of the suggested working dilution to label 10⁶ cells or 100µl whole blood

Clonă

HTA125

Imunogen

Ba/F3 cell line expressing TLR4 (CD284).

Specificitate

This antibody recognises the human Toll like receptor 4 (TLR4) cell surface antigen.TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 molecule.TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS.This antibody has been demonstrated to block activation of monocytes with LPS. The use of a preservative free format of Mouse anti Human CD284 antibody, clone HTA125 (MCA2061EL ) is recommended for functional assays.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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