Anti-TGF beta 1 Antibody

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

50µg

Țintă

TGF beta 1

Applications

WB, IHC-P, ELISA

Reactivity

Human, Mammals, Rabbit, Mouse, Rat

Formulation

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Conjugate

Unconjugated

Host

Rabbit

Clonality

Polyclonal

Product form

Liquid

Concentration

400 µg/ml

Isotype

IgG

Recommended dilutions

ELISA: 1:2,000 - 1:10,000, IHC-P: 5 µg/ml, WB: 1:200 - 1:1,000

Protein Length

8

Secvență

FSSTEKNC

Imunogen

Synthetic peptide corresponding to amino acids 286-293 of the human TGF-beta precursor protein.

Aminoacizi

aa 286 - 293

Specificitate

This antibody recognises human Transforming Growth Factor Beta 1 (TGF-beta1), a 390 amino acid secreted protein belonging to the TGF-beta family.TGF-beta1 is a multifunctional protein that controls proliferation, differentiation and other functions in a wide range of cell types and both positively and negatively regulates many other growth factors. TGF-beta1 also plays an important role in bone remodelling through stimulation of oesteoblastic bone formation causing chemotaxis, proliferation and differentiation in committed osteoblasts. Defects in TGFB1 are the cause of Camurati-Engelmann disease (CED), also known as progressive diaphyseal dysplasia 1.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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