Anti-TAP1 Antibody

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Descriere

Specificații

Brand

Antibodies

Mărime

50µg

Țintă

TAP1

Applications

WB, ELISA, Flow Cytometry, IP

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Conjugate

Unconjugated

Host

Rabbit

Clonality

Polyclonal

Product form

Liquid

Concentration

1 mg/ml

Isotype

IgG

Recommended dilutions

ELISA: 1:10,000, WB: 1:1,000

Molecular weight

Approximately 72 kDa

Imunogen

TAP1 peptide corresponding to the C-terminus of the human protein conjugated to Keyhole Limpet Haemocyanin.

Specificitate

This antibody recognises an epitope within the C-terminal region of human TAP1, also known as transporter associated with antigen processing 1. TAP1 is an ~81 kDa membrane-associated protein which is a member of the ATP-binding cassette (ABC) transporter superfamily and together with the homologous subunit TAP2 forms the functional TAP complex.TAP1 is involved in the transport of antigenic peptides from the cytosol into the endoplasmic reticulum, where they associate with major histocompatibility complex (MHC) class I molecules. These complexes are presented at the cell surface to T-lymphocytes, which identify and remove infected or malignantly transformed cells.Rabbit anti Human TAP1 antibody (AHP1248) does not cross react with human TAP2.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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