Anti-Serum Amyloid P / SAP Antibody [AB12-5A1] (Biotin)

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

Serum Amyloid P/SAP

Applications

ELISA

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.

Conjugate

Biotin

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

100 µg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG2b

Recommended dilutions

ELISA: 1 µg/ml.

Clonă

AB12-5A1

Imunogen

Native SAP purified from human serum.

Specificitate

This antibody recognises Serum Amyloid P-component (SAP) also known as 9.5S alpha-1-glycoprotein, a member of the pentraxin family of proteins. It is synthesized by hepatocytes and secreted into the blood. In humans the levels of SAP range between 20-50 µg/ml. SAP is able to bind to a variety of molecules including apoptotic debris, bacterial polysaccharides, amyloid deposits and bacterial toxins. Phagocytic cells such as monocytes and macrophages then bind the SAP and engulf the material bound to SAP as part of debris clearance. The biotinylated Mouse anti Human SAP antibody, clone AB12-5A1 (MCA6269B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human SAP antibody, clone AB18-4E2 (MCA6268GA) as the capture antibody.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Documentație

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