Anti-PDGF BB Antibody [AB13-3G6] (Biotin)

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

PDGF BB

Applications

ELISA

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.

Conjugate

Biotin

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

100 µg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG2b

Recommended dilutions

ELISA: 1.0 ug/lm

Clonă

AB13-3G6

Imunogen

E. coli derived recombinant human full length PDGF-BB (Ser82-Thr190).

Specificitate

This antibody recognises the homodimer of platelet-derived growth factor subunit B (PDGF-B) also known as PDGF-2, PDGF beta chain and PDGF beta polypeptide. PDGF-BB is a member of the PDGF growth factor family which is made up of 4 isoforms (A, B, C and D). PDGF-BB is a homodimer of the B isoform which is able to bind all three of the PDGF receptors to trigger various signaling pathways including Ras-MAPK, PI3K, PLC?, and JAK. Activation of these pathways lead to transcription of PDGF target genes playing roles in embryogenesis, and in adults under physiological conditions, roles in tissue repair, wound healing and maturation of blood vessels and white adipocytes. The biotinylated Mouse anti Human PDGF-BB antibody, clone AB13-3G6 (MCA6265B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human PDGF-BB antibody, clone AB06-1E10 (MCA6264GA) as the capture antibody.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Documentație

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