Anti-IRF7 Antibody

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Descriere

Specificații

Brand

Antibodies

Mărimi disponibile

50µg · 100µg

Țintă

IRF7

Applications

WB

Reactivity

Human, Mouse, Rat

Formulation

Supplied in phosphate-buffered saline with 0.02% Sodium Azide.

Conjugate

Unconjugated

Host

Rabbit

Clonality

Polyclonal

Product form

Liquid

Concentration

1 mg/ml

Isotype

IgG

Recommended dilutions

WB: 0.5 for 0.1 mg, 1.0 for 50 µg - 1 µg/ml for 0.1 mg, 2 µg/ml for 50 µg

Molecular weight

Approximately 51 kDa in 293 whole cell lysate.

Protein Length

14

Imunogen

A peptide corresponding to 14 amino acids near the C-terminus of human IRF7.

Specificitate

This antibody recognises an epitope within the C-terminal (CT) of human interferon regulatory factor 7 (IRF7), a ~54 kDa transcriptional activator of type I interferons (IFNalpha/beta) in response to local and systemic viral infection. IRF7 is mostly expressed by plasmacytoid dendritic cells (pDC), which differentiate in response to IFNs and virus infection. This then stabilizes the IRF7 protein, in turn leading to increased IFN production.Multiple IRF7 transcript variants have been identified.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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