Anti-Granzyme B Antibody [GB7]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

Granzyme B

Applications

IHC-P, WB

Reactivity

Human

Formulation

Supplied in TRIS Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein A affinity chromatography of tissue culture supernatant.

Isotype

IgG2a

Recommended dilutions

IHC-P 1: 1:50 - 1:200

Clonă

GB7

Imunogen

Recombinant Granzyme B.

Specificitate

This antibody recognises the serine protease Granzyme B, expressed within the granules of cytolytic lymphocytes (CTLs)Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell Granzyme B activates the cascade of caspases that finally results in cell death. Mouse anti Human Granzyme B antibody, clone GB7 has been reported to be suitable for Western Blotting, demonstrating reactivity with recombinant granzyme B and also reactivity with recombinant granzyme H. Human granzymes B and H share ~71% sequence identity by clustal analysis.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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