Anti-Granzyme B Antibody [GB11]

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

Granzyme B

Applications

Flow Cytometry, ELISA, IHC-Fr, IP, IF

Reactivity

Human, Chimpanzee, Monkey, Rhesus Monkey

Formulation

Supplied in TRIS Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein A affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

ELISA: 2 µg/ml - 5 µg/ml, FC 1: 1:10 - 1:100

Clonă

GB11

Imunogen

Purified human Granzyme B.

Specificitate

This antibody recognises the serine protease Granzyme B, important in the induction of apoptosis in target cells by cytolytic lymphocytes (CTLs).Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell, Granzyme B activates the cascade of caspases that finally results in cell death. Mouse anti Granzyme B antibody, clone GB11 is suitable for the detection of Granzyme B expressing cells by flow cytometry. In normal peripheral blood approximately 20% of CD8+ve T cells have been found to express Granzyme B.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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