Anti-CD41 Antibody [MWReg30]

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Descriere

Specificații

Brand

Antibodies

Mărimi disponibile

25µg · 100µg · 250µg

Țintă

CD41

Applications

IP, Flow Cytometry, IHC-Fr

Reactivity

Mouse

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Rat

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

Flow Cytometry: 1:50 - 1:100, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl.

Clonă

MWReg30

Imunogen

Purified murine platelets.

Specificitate

This antibody recognises the mouse integrin alpha IIb subunit CD41. CD41 is a ~125 kDa single pass type 1 transmembrane glycoprotein expressed by platelets, megakaryocytes , mast cells , and hematopoietic progenitors. CD41 forms a heterodimer with CD61.The CD41/CD61 complex is important for platelet adhesion and aggregation acting as a receptor for many extracellular matrix proteins including fibronectin, thrombospondin and vitronectin. Rat anti mouse CD41, clone MWReg30 has been reported to inhibit PMA induced aggregation in vitro and to induce hypothermia in vivo.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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