Anti-CD41 Antibody [MWReg30] (PE)

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Descriere

Specificații

Brand

Antibodies

Mărime

100T

Țintă

CD41

Applications

Flow Cytometry

Reactivity

Mouse

Formulation

Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.

Conjugate

PE

Host

Rat

Clonality

Monoclonal

Product form

Lyophilized

Concentration

Reconstitution dependent.

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl. The Fc region of monoclonal antibodies may bind to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR (BUF041A/BUF041B).

Reconstitution

Reconstitute with 1 ml of distilled water.

Clonă

MWReg30

Imunogen

Purified murine platelets.

Specificitate

This antibody recognises the mouse integrin alpha IIb subunit CD41. CD41 is a ~125 kDa single pass type 1 transmembrane glycoprotein expressed by platelets, megakaryocytes , mast cells , and hematopoietic progenitors. CD41 forms a heterodimer with CD61.The CD41/CD61 complex is important for platelet adhesion and aggregation acting as a receptor for many extracellular matrix proteins including fibronectin, thrombospondin and vitronectin. Rat anti mouse CD41, clone MWReg30 has been reported to inhibit PMA induced aggregation in vitro and to induce hypothermia in vivo.

Storage

Lyophilized: Store at 4°C. Reconstituted: Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Documentație

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