Anti-CD20 Antibody [FMC7] (FITC)

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Descriere

Specificații

Brand

Antibodies

Mărime

100T

Țintă

CD20

Applications

Flow Cytometry

Reactivity

Human

Formulation

Supplied in TRIS buffered glycine with 0.1% Sodium Azide and 0.2% BSA.

Conjugate

FITC

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

Lot Specific

Purification

Gel filtration of ascites.

Isotype

IgM

Recommended dilutions

Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 10⁶ cells or 100µl whole blood

Clonă

FMC7

Imunogen

HRIK cells - human B-Lymphoblastoid line.

Specificitate

This antibody recognises a glycoprotein antigen of ~105 kDa expressed by B lymphocytes. The FMC7 antigen is expressed by peripheral B lymphocytes. recognises a conformational epitope on the CD20 molecule, most likely a multimeric complex of CD20. Identity of CD20 as the antigen recognized by Mouse anti Human B cells antibody, clone FMC7 was further confirmed by strong recognition of recombinant CD20 expressed in hematopoietic and non-haematopoietic cell lines and abolition of binding in CD20 extracellular domain mutations. The recognized epitope has also been shown to be cholesterol dependent.

Storage

Shipped at ambient temperature. Store at 4°C. This product is photosensitive and should be protected from light.

Documentație

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