Anti-Blood Group Antigen H Type 2 Antibody [19-OLE]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

Blood Group Antigen H Type 2

Applications

IF, IHC-P

Reactivity

Human

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

200 µg/ml

Purification

Protein A/G chromatography.

Isotype

IgM

Recommended dilutions

IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Light chain

kappa

Clonă

19-OLE

Imunogen

Mucinous colonic adenocarcinoma.

Specificitate

This antibody recognizes the blood group H type 2 antigens, trisaccharide Fuc1 of human origin. This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. It is expressed on endothelial cells, epithelial cells and granulocytes. Increased expression of this antigen has been observed on some tumor tissues such as gastric carcinomas, urothelial carcinomas, and colon carcinomas.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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