Recombinant Human BDNF Protein

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Specificații

Brand

Antibodies

Mărime

10µg

Țintă

BDNF

Applications

Functional Assays

Product form

Lyophilized

Concentration

100 µg/ml after reconstitution.

Purity

>98% (by SDS-PAGE and HPLC).

Reconstitution

Reconstitute with 100 µl of distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution.

Expression system

Escherichia coli

Nature

Recombinant

Protein species

Human

Endotoxin level

< 1 EU/µg

Specificitate

Brain-derived neurotrophic factor (BDNF) is a potent neurotrophin and member of the NGF-beta family, secreted from dense core vesicles, which promotes the growth, differentiation and survival of neurons within, or directly connected to, the central nervous system.BDNF signals through binding to the high affinity receptor trkB, and also binds to the low affinity neurotrophin receptor LNGFR. BDNF is involved in the modulation of short-term synaptic function and in the formation of long-term memory, and reduced levels of BDNF are seen in patients with Alzheimer's and Huntington disease (Girota et al. 2022).

Storage

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Documentație

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