Native Human Cardiac Troponin I Protein

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Specificații

Brand

Antibodies

Mărime

10µg

Țintă

Cardiac Troponin I

Applications

ELISA

Formulation

Supplied in 7M Urea with 5mM EDTA, 20mM TRIS, and 15mM Mercaptoethanol.

Product form

Liquid

Concentration

1 mg/ml

Purity

> 98% (by SDS-PAGE).

Nature

Native

Protein species

Human

Source

Human heart.

Specificitate

Human cardiac troponin I is the inhibitory subunit of troponin involved in confering calcium sensitivity to muscle actomyosin ATPase activity. Mutation of the TNN13 gene can lead to familial hypotrophic cardiomyopathy 7 (CMH7), a hereditary heart condition characterized by asymetric ventricular hypertrophy (Kimura et al. 1997). Other cardiomyopathies also occur as a result of mutations in the TNN13 gene (UniProt : P19429).

Storage

Store undiluted at -20°C only, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Documentație

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