Native Chlamydia trachomatis Protein

Pe scurt

Specificații

Brand

Antibodies

Mărime

1mL

Țintă

Chlamydia trachomatis

Applications

Immunoassay, ELISA

Formulation

Supplied in Phosphate Buffered Saline.

Product form

Liquid

Concentration

4.9 mg/ml

Recommended dilutions

PIP004 should be sonicated immediately before use to ensure the preparation is uniform. The product may be used in a variety of IA formats or may be further purified to meet the requirements of a particular assay format.

Nature

Native

Protein species

Bacterial

Specificitate

Chlamydia trachomatis is a nonmotile, Gram-negative human pathogen. It undergoes a unique biphasic developmental cycle, forming elementary bodies extracellularly and distinctive intracellular inclusions. The elementary body is infectious but metabolically inactive, cannot replicate and lacks detectable peptidoglycan. The major outer membrane protein (MOMP) comprises a large percentage of the outer membrane and is a transmembrane protein with type, species and genus reactive epitopes. The outer membrane also carries a heat stable lipopolysaccharide containing the reactive epitopes used for genus specific serological tests. There is structural similarity and antigenic cross-reactivity between chlamydial and other Gram-negative LPS moieties.Chlamydia trachomatis is a common sexually transmitted bacterium. Chlamydia infection may cause proctitis, urethritis, trachoma (an eye infection and the leading cause of blindness worldwide) and infertility in both sexes. Prostatitis and epididymitis may occur in men and in women infection might lead to acute or chronic pelvic pain, pelvic inflammatory disease, cervicitis and ectopic pregnancy. In neonates the pathogen may cause trachoma and pulmonary complications.Chlamydia trachomatis (PIP004 contains a high concentration of elementary bodies and chlamydial components in phosphate buffered saline. Residual host cellular material is present.

Storage

Short term: Store undiluted -20°C. Long term: Store undiluted at -70°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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