Cyanine 7 NHS ester

Amine reactive Cyanine 7, near infrared fluorescent dye, an improved analog of Cy7®. NIR fluorophores can be used to take advantage of near infrared window of biological tissues - increased transparency of tissues in this spectral region allows to carry out in vivo imaging. This reagent can be utilized to produce Cyanine 7-labeled biomolecules for subsequent use in various in vivo research, and drug design related experiments. The structure of Cyanine 7 features rigidized design of central polymethyne chain. This molecular reinforcement increases quantum yield by 20% compared with the parent structure, increasing fluorescence brightness. This reagent requires an organic co-solvent for the labeling reaction. Water-soluble Cyanine 7 NHS ester is also available, and recommended for protein NIR labeling.