Anti-ZNF276 Antibody [PCRP-ZNF276-1A5] - BSA and Azide free

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

ZNF276

Applications

ELISA, IP, Flow Cytometry, IF

Reactivity

Human

Formulation

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein A/G chromatography.

Isotype

IgG2b

Recommended dilutions

IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml

Molecular weight

67 kDa

Clonă

PCRP-ZNF276-1A5

Imunogen

Recombinant full-length human ZNF276 protein.

Specificitate

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF276 is a 614 amino acid protein containing five C2H2- type zinc fingers and one zinc finger associated (ZAD) domain. Due to a loss of heterozygosity at the chromosomal location of the gene encoding ZNF276 in sporadic breast cancers, the ZNF276 gene has been targeted as a possible breast cancer tumor suppressor. The FANCA gene, which encodes a DNA repair protein, is situated at the same chromosomal location as the ZNF276 gene, suggesting a possible involvement of ZNF276 in the progression of Fanconi anemia, an autosomal recessive disorder which is caused by mutations in the gene encoding FANCA. There are two isoforms of ZNF276 that exist as a result of an alternative splicing event.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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