Anti-XIAP Antibody

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

XIAP

Applications

WB, IHC-P

Reactivity

Human, Mouse

Formulation

Supplied in phosphate-buffered saline with 0.02% Sodium Azide.

Conjugate

Unconjugated

Host

Rabbit

Clonality

Polyclonal

Product form

Liquid

Concentration

1 mg/ml

Isotype

IgG

Recommended dilutions

IHC-P 1: 2 µg/ml, WB: 0.5 µg/ml - 2 µg/ml

Protein Length

13

Imunogen

Synthetic peptide corresponding to 13 amino acids within the C-terminus of human XIAP.

Specificitate

This antibody recognises human X-chromosome linked inhibitor of apoptosis (XIAP). XIAP is an endogenous inhibitor of cell death, which functions by suppressing caspases 3, 7, and 9. The protein is also reported to play a a role in the activation of NF kappa B and the regulation of cyclins and cyclin-dependent kinase inhibitors (CDKIs). Regulators of XIAP activity include XAF-1 and Smac. Rabbit anti Human XIAP antibody detects a band of approximately 57 kDa in human kidney lysates.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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